Home >> RX Products >> Rifadin, Rofact (Rifampin)
Rifadin, Rofact
Generic Name: rifampin (RIF am pin)
Brand Names: Rifadin, Rimactane
Rifadin : Important Information
- Take all of the medication that has been prescribed for you even if you begin to feel better. Your symptoms may begin to improve before the infection is completely treated.
- Call your doctor immediately if you experience a fever, chills, muscle and bone pain, a headache, excessive tiredness or weakness, loss of appetite, nausea, vomiting, a sore throat, unusual bleeding or bruising, yellow skin or eyes, a rash, or itching.
- Take on an empty stomach 1 hour before or 2 hours after meals.
- This medication may decrease the effectiveness of birth control pills. Talk to your doctor about using another form of birth control during treatment.
What is Rifadin
- It is an antibiotic. It prevents bacteria from multiplying in your body.
- Used to treat and to prevent tuberculosis (TB).
- This medication may also be used to eliminate a bacteria that can cause meningitis (and other infections) from your nose and throat, even if you do not have an infection. Treatment with this medication prevents you from spreading this bacteria to others who may become ill.
What to Discuss before Using
- Before taking this medication, tell your doctor if you:
- have ever had an allergic reaction to rifampin
- have liver disease
- have porphyria
- You may not be able to take this medication, or you may require a special dosage or monitoring during treatment if you have any of the conditions listed above.
- This medication is in the FDA pregnancy category C. This means that it is not known whether it will harm an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant.
- This medication passes into breast milk and may harm a nursing baby. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.
Rifadin Dosage Method
- Take exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.
- Take each dose with a full glass (8 ounces) of water.
- Take on an empty stomach 1 hour before or 2 hours after meals.
- Take all of the medication that has been prescribed for you even if you begin to feel better. Your symptoms may begin to improve before the infection is completely treated.
- For the treatment of tuberculosis, this medication is usually combined with one or more other tuberculosis medicines.
- Store at room temperature away from moisture and heat.
Miss a dose: Problems?
Take the missed dose as soon as you remember. However, if it is almost time for your next regularly scheduled dose, skip the missed dose and take the next one as directed. Do not take a double dose of this medication.
Rifadin Overdose?
- Seek emergency medical attention.
- Symptoms of an overdose include nausea, vomiting, tiredness, abdominal pain, yellow skin or eyes, and unconsciousness.
Avoid During Treatment
- Do not wear contact lenses while taking this medication. This medicine may turn your tears, sweat, saliva, urine, feces, and contact lenses a red-orange color. This effect may be permanent on contact lenses.
- This medication may decrease the effectiveness of birth control pills. Talk to your doctor about using another form of birth control during treatment.
Rifadin Side Effects
- If you experience any of the following serious side effects, stop taking this medication and seek medical attention or contact your doctor immediately:
- an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives)
- fever, chills, or a sore throat
- muscle or bone pain
- excessive tiredness or weakness
- a headache
- nausea, vomiting, diarrhea, or loss of appetite
- unusual bruising or bleeding
- little or no urine
- yellow skin or eyes
- a rash or itching
- Other, less serious side effects may be more likely to occur. Continue to take this medication and talk to your doctor if you experience:
- red-orange coloration of tears, sweat, saliva, urine, or feces
- mild tiredness or weakness
- Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
What other drugs to avoid while undergoing treatment
- Rifampin may decrease the effects of the following drugs:
- acetaminophen (Tylenol, others)
- blood thinners such as warfarin (Coumadin)
- barbiturates such as phenobarbital (Luminal, Solfoton), amobarbital (Amytal), secobarbital (Seconal), and butabarbital (Butisol)
- benzodiazepines such as alprazolam (Xanax), diazepam (Valium), lorazepam (Ativan), and temazepam (Restoril)
- beta-blockers such as atenolol (Tenormin), propranolol (Inderal), and metoprolol (Lopressor)
- heart medicines such as digoxin (Lanoxin), disopyramide (Norpace), quinidine (Quinora, Quinidex, Cardioquin, others), mexiletine (Mexitil), tocainide (Tonocard), verapamil (Calan, Verelan, Isoptin), and enalapril (Vasotec)
- corticosteroids such as prednisone (Deltasone, Orasone, Meticorten), prednisolone (Delta Cortef, Prelone, others), methylprednisolone (Medrol), and betamethasone (Celestone)
- sulfonylureas such as glipizide (Glucotrol), glyburide (Micronase, Diabeta, Glynase), chlorpropamide (Diabinese), tolbutamide (Orinase), and tolazamide (Tolinase)
- sulfa medicines such as sulfamethoxazole (Bactrim, Septra, Gantanol, Azo-Gantanol), and sulfisoxazole (Gantrisin, Azo-Gantrisin)
- estrogens such as Premarin, Ogen, Estrace, Menest, Estratab, Ortho-Est, and others
- HIV medicines such as delavirdine (Rescriptor), saquinavir (Invirase, Fortovase), ritonavir (Norvir), nelfinavir (Viracept), and others
- oral birth control pills such as Triphasil, Ortho-Novum, Ortho-Cyclen, Ortho-Tri-Cyclen, Ovral, Lo/ Ovral, Desogen, Nordette, Levora, Levlen, Tri-Levlen, Nelova, Norinyl, Brevicon, Ovcon, Loestrin, Demulen, and others
- phenytoin (Dilantin), ethotoin (Peganone), and mephenytoin (Mesantoin)
- ketoconazole (Nizoral), itraconazole (Sporanox), and fluconazole (Diflucan)
- methadone (Dolophine)
- theophylline (Theolair, Theo-Dur, Theochron, Theo-Bid, others)
- clofibrate (Atromid-S)
- cyclosporine (Sandimmune, Neoral)
- Drugs other than those listed here may also interact. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.
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